Brain & Nerve Health
How does RLT help?
There appears to be neuroprotective effects of laser and light-emitting diodes (LED) in diverse neurological conditions, such as traumatic brain injury (TBI), ischemic stroke, Alzheimer’s disease, Parkinson’s disease, as well as age-related cognitive decline. Besides these therapeutic effects at the molecular level, there is also considerable evidence of changes occurring at the behavioral level such as cognitive enhancement, antidepressant effects, and improved sleep.
How does this improve my health & wellness?
The brain, along with the heart and muscle, are the tissues with the greatest mitochondrial density. Mitochondria, which are extremely important for our health, longevity and energy production, respond exceptionally well to red/NIR light. Thus, the brain and overall cognitive function (ie. Alzheimer's disease) has a great capacity to heal with RLT.
It is believed that impaired cerebral vascular perfusion is the one of the first manifestations of most brain disorders. RLT can increase the neuronal nitric oxide content, increase the vessel diameter, and improve cerebral blood flow (CBF). Therefore, it could be considered that RLT of specific areas of the brain potentially affects regional CBF.
Like the brain, the nerves benefit from enhanced mitochondrial function that helps improve energy production. This increased energy leads to accelerated regeneration of injured peripheral nerves along with improved axonal number and distance of nerve axon regrowth.
What does the research show?
"Transcranial laser therapy (TLT) showed an increase in ATP levels, mitochondrial function, and c-fos suggesting an overall improvement in neurological function. These studies suggest that TLT is a potential candidate for treatment of Alzheimers disease.”
De Taboada, Luis & Yu, Jin & El-Amouri, Salim & Gattoni-Celli, Sebastiano & Richieri, Steve & McCarthy, Thomas & Streeter, Jackson & Kindy, Mark. (2011). Transcranial Laser Therapy Attenuates Amyloid-beta Peptide Neuropathology in Amyloid-beta Protein Precursor Transgenic Mice. Journal of Alzheimer's disease : JAD. 23. 521-35. 10.3233/JAD-2010-100894.
"This treatment (near-infrared light) also significantly reduced dopaminergic neuronal loss in the injected substantia nigra and preserved dopaminergic fibers in the ipsilateral striatum. These beneficial effects were sustained for at least 6 weeks after discontinuing the treatment. Together, our data point to photobiomodulation as a possible therapeutic strategy for the treatment of Parkinson's Disease and other related synucleinopathies.."
Oueslati A, Lovisa B, Perrin J, Wagnières G, van den Bergh H, Tardy Y, Lashuel HA (2015) Photobiomodulation suppresses alpha synuclein-induced toxicity in an AAV-based ratgeneticmodelofParkinson ’s disease. PLoS One 10(10): e0140880
"Transcranial LLLT has been shown to significantly improve outcome in acute human stroke patients when applied approximately 18 hours after the stroke occurs over the entire surface of the head, regardless of the stroke location."
Lampl Y, Zivin JA, Fisher M, et al. Infrared laser therapy for ischemic stroke: a new treatment strategy: results of the NeuroThera Effectiveness and Safety Trial-1 (NEST-1). Stroke. 2007; 38:1843–1849.
"These results suggest that LLLT could be applied in cases of general cognitive impairment in elderly persons."
Michalikova S, Ennaceur A, van Rensburg R, et al. Emotional responses and memory performance of middle-aged CD1 mice in a 3D maze: effects of low infrared light. Neurobiol Learn Mem. 2008; 89:480–488.
"Roch-kind et. al. demonstrated that LLLT applied simultaneously to the injured sciatic nerve and the corresponding segment of the spinal cord accelerates the process of regeneration of the injured peripheral nerve."
Rochkind S, Barr-Nea L, Bartal A, et al. New methods of treatment of severely injured sciatic nerve and spinal cord. An experimental study. Acta Neurochir Suppl (Wien). 1988; 43:91–93.
"Light therapy significantly improved the average length of axonal regrowth and increased the total axon number. These results suggest that light may be a promising therapy for human spinal cord injury."
Wu X, Dmitriev AE, Cardoso MJ, et al. 810 nm Wavelength light: an effective therapy for transected or contused rat spinal cord. Lasers Surg Med. 2009; 41:36–41.
**While the current scientific research seems to indicate many positive benefits of RLT in relation to brain and nerve health, there is still an appreciable necessity for more extensive research to be conducted in this area, including double-blind RCT (randomized controlled trials), to provide a more comprehensive, robust overview that will further elucidate the optimal parameters and appropriate uses of RLT, which will ultimately lead the most safe and efficacious uses for individuals dealing with brain and nerve disorders.
Suggested use of RLT for
Brain & Nerve Health
3 - 7x/week
Stroke & TBI:
2 - 7 min. @ 6" away
Peripheral Nerve Injury:
45 - 75 min. @ 6" away, daily for 1 - 2 weeks
Spinal Cord Injury
3 hours @ 6" away, daily for 1-2 weeks
NIR only, as NIR penetrates deeper than red light. In order to reach the brain tissue, NIR light is required and red light does not add any additional benefit.
*For optimal results, we recommend no more than 15 - 20 minutes of total treatment time per day